RNAs produced in cells can be released from the cells and may mediate communication between cells. Small RNAs, including microRNAs (miRNAs) and fragments of larger RNAs, can be detected in human biofluids and may be useful biomarkers for disease. After completing her undergraduate studies at UCSC, Paula Godoy joined the Erle lab as a research associate and collaborated closely with Andrea Barczak, Prescott Woodruff, and organizers of several clinical cohorts to compare small RNA  profiles from 12 different human biofluids. Paula found that all 12 biofluids have diverse small RNA repertoires, that the relative abundance of miRNA to tRNA-derived RNA fragments differs markedly across biofluids, that biofluid miRNA profiles are generally similar (with some miRNAs being notable exceptions), and that there are large differences in tRNA-derived RNAs between biofluids. This work has now been published in Cell Reports, and first author Paula Godoy is now a PhD student in the Computational and Systems Biology program at Washington University. Congratulations to Paula and the team!